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shout out to thyroid issues for fucking me over my tummy hurts and my heads killig me. am alost aways feelings sick
tsh but it's not the secret history it's actually thyroid-stimulating hormone
Jokeâs on the ableist people though, in my case. I want to die, have for years. I hate being a burden so very much, especially because my disabilities arenât obvious and look like laziness even to me. I would have killed myself long ago if I didnât have family who would grieve.
I hate how often some (typically abled) people will go âwell, if you canât [get a specific support], then what?â when it comes to disabilities. As if itâs a âgotchaâ moment. And then act like youâre exaggerating when you answer that question honestly.
Disabled people often die from a lack of support. A lot of disability aids are not a luxury, but a basic need in order to live.
âWell what happens ifââ people die. People hurt themselves. People hurt others. Disabled people donât magically become abled if our needs arenât met.
If a bedbound quadriplegic is caught in a housefire, and thereâs nobody there to save them, theyâll probably die. They wonât magically become able-bodied out of sheer will.
If a nonspeaking/nonverbal autistic is denied access to alternative methods of communication, theyâll suffer in silence. They wonât spontaneously become capable of speech.
Disabled people are disabled all the time. Our disabilities donât go away just because theyâre inconvenient, or if weâre in danger.
TSH levels
Free T4 (fT4) levels
Measurements of total T4 + T3 used to be common however detects both bound and free T3 + T4
Elevated total T4 may occur in healthy individuals if there is an increase in binding protein concentrations
Reliable tests now exist for free T4 + T3
T3 = 3.9-6.7 pmol/L
T4 = 12-22 pmol/L
Thyroid-stimulating hormone
Produced by the pituitary gland, not the thyroid, however:
TSH levels are controlled by negative feedback â can be indication of thyroid function (changes in T3+T4 will result in changes in TSH to try compesate)
TSH levels greatly elevated in hypothyroidism â >10 fold increase over reference values
More sensitive marker than decreased fT4 - increased TSH occurs before fT4 decreases
TSH levels greatly supressed in hyperthyroidism
Low concentrations can also occur in non-thyroidal illness
TSH measurement is the first-line test of thyroid function.
Free T4 + T3 Measurements
Desirable as free hormone is clinically relevant
Total levels can change under conditions that alter thyroxine-binding globulin (TBG) levels e.g. pregnancy
Large changes in TBG may still affect fT4 + fT3 levels
fT3 levels often normal in hypothyroidism
fT3 levels usually raised more than fT4 levels in hyperthyroidism
Unless complicated by an illness effecting conversion of T4 to T3
Therefore: â fT4 levels are a better indication of hypothyroidism
fT3 levels are a better indication of hyperthyroidism